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This problem is generally due to one or more profiles under HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows NT\CurrentVersion\ProfileList with missing ProfileImagePath. Please note before using the registry editor, if you edit any settings incorrectly, the system may fail to work properly.
To check whether you have missing profiles:
1. Open regedit, navigate to the above registry key. (HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows NT\CurrentVersion\ProfileList). Expand the list

2. Click on each of the profiles listed. The first 3 profiles should have ProfileImagePath value of
%SystemRoot%\System32\Config\SystemProfile, %SystemRoot%\ServiceProfiles\LocalService, and %SystemRoot%\ServiceProfiles\NetworkService respectively.

3. Starting from the 4th profile, the ProfileImagePath should contain path to the user profiles on your machine, such as C:\users\Christine

4. If one or more of the profile has no profile image, then you have missing profiles.

To work around this, delete the profile in question (Caution: The registry contains critical settings that are necessary for your system to function properly. Take extra caution while making changes)

1. First, export the ProfileList key for safekeeping. (Right click on the key, choose “Export”, and save it to the desktop.)
2. Right click on the profile in question, choose delete.
3. Try backup again.

Windows does not create "Contacts" and "Searches" directories which Windows backup expect to be present. As a workaround, please try the following:

1. Launch Change backup settings.
2. Choose the same backup target and proceed to next page.
3. Select "Let me choose".
4. Expand the user Mcx1-NEO node in the treeview. Expand "Additional locations".
5. Exclude the Contacts and Searches directories for the user.
6. Proceed with configuration and save settings.

Here’s to Good Karma