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Most of today's viruses (Trojan horses, I-Worms, Worms, etc) create their own files which contain nothing but the body of the virus. In such cases the only way to remove the infection is to delete the infected file. When the file is moved to the AVG Virus Vault it is deleted from its original location, coded, and then saved in a non-executable file in a hidden folder. Your PC is then no longer infected.
If you are not missing any data file and your applications are running correctly, you can delete these files from the AVG Virus Vault.
To delete individual files from the AVG Virus Vault:
Open the AVG User Interface.
On the History menu, click Virus Vault.
Select the file you want to delete.
Click Delete.
Or you can delete all AVG Virus Vault contents in one go:
Open the AVG User Interface.
On the History menu, click Virus Vault.
Click Empty Vault.

Here’s to Good Karma

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You can delete it and it wont harm your computer but I always just leave them in the virus vault where they can do no more damage, either way is fine, A virus can not cause any problems once they are in the vault, the are held captive there,, As mentioned above its best to leave it in quarantine for a while and make sure it is not a normal file that avg has misidentified, that can and does happen sometimes, SG