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It is not recommended to install multiple security programs on the same computer but now that you’ve made sure that the system has no virus, one likely cause for the hard drive losing space so rapidly (unless a lot of programs have been installed on it) could be backup settings.

1. Make sure the system is not creating automatic backups on the internal hard drive itself. You can check the settings through the ‘Backup and Restore’ option in the Control Panel. If that is the case, you can refer to http://www.sevenforums.com/tutorials/628-backup-user-system-files-delete-backups.html for steps to manage or delete backups.
2. Turn ‘System Protection’ off and then turn it on. You can refer to http://windows.microsoft.com/en-us/windows7/Turn-System-Restore-on-or-off for the steps to do so. Check if that makes a difference.
Warning: Doing so deletes all existing restore points.
3. Go to ‘Start> Computer’ and check the size of each folder by right clicking it and clicking ‘Properties’. If a folder is abnormally large check the contents and do the same with any large sub-folders if required. If you are not sure about the function of the folder, please repost and mention the name and path of the folder.
4. Uninstall programs that are not required (not likely to be many as you just reformatted the hard drive).

Hope it helps.

Here’s to Good Karma